2530 South Commerce
Ardmore, OK 73401
Phone: (580) 223-5070

Crisis: (800) 522-1090
EMERGENCY NUMBERS

Alzheimers Disease and other Cognitive Disorders
Resources
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Deep Brain 'Zap' Restores Vivid Memories to Alzheimer's PatientsHow to Protect a Loved One With Dementia During a Heat WaveToo Much Napping May Signal Alzheimer'sDepression, Alzheimer's Might Be Part of Same Process in Some Aging Brains: StudyStay Social to Help Cut Your Odds of DementiaBlood Test May Spot Brain Changes of Early Alzheimer'sClues to Why Women Have Higher Odds for Alzheimer'sA New and Better Way to 'Stage' Alzheimer's Patients?At Risk for Alzheimer's? Exercise Might Help Keep It at BayHealthy Living Can Cut Odds for Alzheimer's in People at Genetic RiskHormone Treatment for Prostate Cancer Linked to Heightened Alzheimer's RiskAlzheimer's Genes Might Show Effects in Your 20sWidely Prescribed Class of Meds Might Raise Dementia RiskCancer Survivors May Have Lower Odds for DementiaCommon Blood Pressure Med Might Help Fight Alzheimer'sEducation, Intelligence Might Protect Your BrainOpioids Put Alzheimer's Patients at Risk of Pneumonia: StudyFor Some, Trouble Tracking Finances Could Be Sign of DementiaIt's Never Too Late for New Brain CellsHigh LDL Cholesterol Tied to Early-Onset Alzheimer'sDoes Hormone Therapy for Prostate Cancer Raise Dementia Risk?Could Alzheimer's Spread Like Infection Throughout the Brain?Newly Discovered Illness May Cause Nearly 1 in 5 Dementias, Experts SayFinancial Scammers Often Prey on People With Early DementiaMore Alzheimer's Drug Trial Failures: Are Researchers on the Wrong Track?Gum Disease Shows Possible Links to Alzheimer'sBrain Scans Spot, Track Alzheimer'sFewer Periods May Mean Higher Dementia RiskOnly Spoken Words Processed in Newly Discovered Brain RegionRate of U.S. Deaths Tied to Dementia Has More Than DoubledEven Distant Relatives' History Could Up Your Alzheimer's RiskHealthy Diet Might Not Lower Dementia RiskDementia May Strike Differently, Depending on RaceHormone Therapy Linked to Slight Rise in Alzheimer's RiskSleep Apnea May Be Linked With Alzheimer's MarkerScientists Find 5 New Genes That Sway Alzheimer's RiskActive Brain and Body Are Powerful Weapons Against DementiaAre Hearing Loss, Mental Decline Related?Education No Match Against Alzheimer'sCould Gut Bacteria Be Linked to Dementia Risk?Plunging Temperatures a Threat to People With Alzheimer'sBlood Test Might Yield Early Warning of Alzheimer'sFrailty a Risk Factor for DementiaAHA: Blood Pressure May Explain Higher Dementia Risk in BlacksSleep Patterns May Offer Clues to Alzheimer'sDoes Alzheimer's Unfold Differently in Black Patients?Health Tip: Caring for a Person With Alzheimer'sCan Alzheimer's Be Spread? Mouse Study Hints It's PossibleDoctors' Office Dementia Tests Are Often Wrong: StudyAlzheimer's Vaccine Shows Promise in Mice
Questions and AnswersVideosLinksBook Reviews
Related Topics

Aging & Geriatrics
Memory Problems
Elder Care

Clues to Why Women Have Higher Odds for Alzheimer's

HealthDay News
by -- Robert Preidt
Updated: Jul 17th 2019

new article illustration

WEDNESDAY, July 17, 2019 (HealthDay News) -- Rates of Alzheimer's disease are higher in women than in men, and researchers now think they know why.

A team from Vanderbilt University Medical Center, in Nashville, Tenn., has identified gender differences in how the Alzheimer's-related protein tau spreads in the brain.

Research suggests that tau spreads through the brain like an infection, moving from neuron to neuron and turning other proteins into abnormal tangles that result in the death of brain cells.

In this study, investigators used data from positron emission tomography (PET) scans of healthy people and patients with mild mental (cognitive) impairment to create a graph analysis of how tau spreads.

"It's kind of like reconstructing a crime scene after a crime. You weren't there when it happened, but you can determine where an intruder entered a house and what room they entered next," said lead investigator Sepi Shokouhi, an assistant professor of psychiatry and behavioral sciences.

"The graph analysis does something similar to show how tau spreads from one region to another," Shokouhi explained in a center news release.

The researchers found that the structure of tau networks is different in men and women, with women having a larger number of "bridging regions" that connect various areas of the brain.

This may enable tau to spread more easily between brain regions, increasing the speed at which it accumulates and putting women at greater risk for Alzheimer's disease, the investigators theorized.

The study was presented Tuesday at the Alzheimer's Association International Conference, in Los Angeles. Data presented at conferences is usually considered preliminary until published in a peer-reviewed medical journal.

Further research is needed to confirm that women have an accelerated spread of tau. If it's proven, then sex-specific approaches may be needed to prevent Alzheimer's, according to the researchers. This could include earlier treatment, lifestyle interventions and/or remedial help for memory.

"Understanding how different biological processes influence our memory is a really important topic," Shokouhi said.

More information

The U.S. National Institute on Aging has more about Alzheimer's disease.